A Monoclonal Antibody against Wnt-1 Induces Apoptosis in Human Cancer Cells
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چکیده
منابع مشابه
A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells.
Aberrant activation of the Wingless-type (Wnt)/beta-catenin signaling pathway is associated with a variety of human cancers. Little is known regarding the role that Wnt ligands play in human carcinogenesis. To test whether a Wnt-1 signal is a survival factor in human cancer cells and thus may serve as a potential cancer therapeutic target, we investigated the effect of inhibition of Wnt-1 signa...
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ژورنال
عنوان ژورنال: Neoplasia
سال: 2004
ISSN: 1476-5586
DOI: 10.1016/s1476-5586(04)80048-4